Pass the ASCP Molecular Biology Exam

How to Pass the ASCP Molecular Biology Exam Action Plan

How to Pass the ASCP Molecular Biology Exam by MLSIAcademy

Which study technique will assist you to pass the ASCP molecular biology exam from the first sitting?
It is a concern for all the applicants of MB/SMB ASCP.
Because the majority of students implement smart techniques to pass the exam with smart study resources.
But passing the ASCP molecular biology exam is different from all those couple of exams that you have taken to reach your current position.

Here, you have to think outside of the box, because if you know the strategy to study smarter than harder, you will pass the ASCP with appreciated marks.

 Here are some effective studies tips that help you ace your preparation journey to get the ASCP molecular biology certificate for MB ASCP or SMB ASCP with ease.

How to Pass the ASCP Molecular Biology Exam Step by Step Action Plan

Total Time: 2 minutes

Know the ASCP Molecular Biology Exam Content Guidelines

ASCP Molecular Biology Exam Content Area by MLSIAcademy

Four subjects are determined by the board of certification for the ASCP molecular biology exam.
The ASCP Board of Certification determines the four subjects for the ASCP molecular biology exam.
The subjects are molecular science, molecular techniques, lab operation, and application of molecular testing.
Getting knowledge from all is vital to passing the ASCP molecular exam.
The board chooses the different percentages of questions for each exam so you should focus on each based on its question percentages.
The following are question percentages for each content area;
Molecular Science: 5-10% for SMB ASCP, 20-25% for MB ASCP
Application of Molecular Testing: 35-40% for SMB ASCP, 30-35% for MB ASCP
Lab operation: 25-30% for SMB ASCP, 15-20% for MB ASCP
Molecular techniques: 30-35% for both

See ASCP-recommended Preparation Resources

The ASCP BOC supports the candidate with all necessary preparation resources.
You can utilize these resources if you have enough time for preparation.
Some resources are described below:
Text Books
  Molecular Diagnostics: Fundamentals, Methods, & Clinical Applications (3rd edition)
Molecular Pathology in Clinical Practice (2nd edition)
Thompson & Thompson Genetics and Genomics in Medicine (9th edition)
DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer (3rd edition).
Clinical Genomics: A Guide to Clinical Next Generation Sequencing.
Molecular Microbiology: Diagnostic Principles and Practice (3rd edition)
 Mathematics for the Clinical Laboratory (4th edition)
ACMG Clinical Laboratory Standards for Next-Generation Sequencing.
Guidelines for Validation of Next-Generation Sequencing-Based Oncology Panels: A Joint Consensus Recommendation of the Association for Molecular Pathology and College of American Pathologists
dPCR: A Technology Review.
Online Association
Association for Molecular Pathology (AMP) “Molecular in My PocketTM” Reference Card Series
ACMG Technical Standards for Clinical Genetics Laboratories (2021 Revision)
WHO Classification of Tumors Online
American Society for Microbiology (ASM) Molecular Resources
American Society for Histocompatibility and Immunogenetics (ASHI) Educational Resources
Clinical and Laboratory Standards Institute (CLSI)
College of American Pathologists (CAP)

Understand the ASCP Molecular Biology Exam Format

Understanding the MB/SMB ASCP exam format is essential to pass the ASCP molecular biology exam.
Both exams of ASCP molecular biology are composed of 100 questions; all are MCQs with one right answer for both MB and SMB.
The given time frame for both exams is 2.5 hours.
It is formulated by CAT (Computer Adaptive Testing); A computer that is packed with a series of easy and difficult questions.
This computer displays the different difficulty levels of questions based on the examinee’s answer.
If you answer the question correctly, the next question will be a little tougher, if your answer is again correct,  the computer will show more tougher than the previous one; and so on.
The difficulty level of your questions determines your pass or fail result.

Depend on the Unified Study Guide

If you implement the all-in-one and conclusive study guide for the preparation of ASCP molecular biology exam, you can ace it with ease.
Following are features of good study guide that you must keep in mind when you are going to purchase it;
Your selected study guide must be comprehensive and summarize the entire content area in one cover.
It must remove the fluff and condense long-form information into short
Make the content easy with different techniques, including visual illustrations, Q&A, simple words, etc.
You must also check the number of its edition

Subscribe to Online Prep Course

Subscription to the online ASCP preparation package is your need to pass the ASCP molecular biology exam.
But which one should you subscribe from many?
The MLSIA ASCP molecular biology course program by is best because it offers all the necessary tools for your ASCP exam preparation.
Here are the tools that you will get from MLSIAcademy
Live online classes that are delivered by ASCP-certified professors
You can also get the recordings if you miss or skip any part of the class
All-in-one study guide that are a mixture of all BOC-recommended resources
QBanks, flashcards, Q&A, Mock tests, and CAT format tests.

A Motivated Study Schedule

Your effective study schedule and your stickiness with it help you a lot to pass the ASCP molecular biology exam.
You must follow the rules of How much, How long, When, and What to create your study schedule.
Make sure to divide your time among all the content areas based on their exam level and the size of the content.
Keep time for practice and refreshments.

Organized the Study Environment

An organized study environment is a peaceful space that encourages you to sit and study. You must organize the space where you sit for study.
Arrange the table and chairs so you can sit comfortably.
Arrange enough light that does not disturb your eyesight.
Make sure to remove all disturbance, noise, etc.
If you are facing noise that can slow your learning process, you must use voice cancelation devices, like headphones, etc.

Practice your Learning

You cannot learn anything until you pass it through the practicing process.
Practice makes perfect, so do it patiently until you get a command of learning.
Practice helps in information retention and this information stays with you for a long time.
You will get better results if you continue your practice with pen and paper.
You must use the MLSIA ASCP molecular biology QBank to practice and know your knowledge gap.

Use Flashcards

The flashcards are little pieces of information that are spread on cards.
This tiny piece of information is easily digested in the mind and enters in long-form memory.
Because the ASCP MB/SMB exam is composed of MCQs, hence, flashcard information may be valuable.

Booking the ASCP Exam

You must apply for the ASCP exam when you are 100% ready to take it.
The right time to apply is when you have covered 90% of your syllabus.

ASCP Final Day Tips

You should get up early in the morning and take a shower to refresh your mind
Take enough sleep
Eat enough food and make sure to eat the food that stays in your stomach for at least 4-5 to five hours.
Reach the exam center before starting the exam at least one hours
Respect the exam center rules and regulations
After starting the exam, concentrate on your computer screen, read the displayed questions carefully, and choose the best answer.
Keep duration in mind and try to handle all in the given time frame.


  • MLSIA Molecular Biology Course


  • ASCP Molecular Biology Live Classes
  • ASCP Molecular Biology Recordings
  • ASCP Molecular Biology Study Guide
  • ASCP Molecular Biology Practice Q&A

Materials: ASCP Molecular Biology PDF ASCP Molecular Biology Video Classes

(FAQs) for How to Pass the ASCP Molecular Biology Exam

How can I pass the ASCP molecular biology exam?

You can pass the ASCP molecular exam by using the best study tools and techniques.

Which exam content area does the ASCP BOC determine for the ASCP MB/SMB exam?

The exam content areas for the ASCP molecular exam are molecular science, lab operation, molecular techniques, and application of molecular testing.

What is the application fee for MB ASCP and SMB ASCP?

The application fee for MB ASCP is $250 and for SMB ASCP, it is $300.

Does the ASCP BOC offer the ASCP molecular certificate for international candidates?

Yes, of course, these certificates are MB ASCPi and SMB ASCPi

Resources: ASCP BOC.